Joint and microRNA

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概要

• 論文の詳細を見る

•   MicroRNAs (miRNA) play a key role for morphogenesis or various diseases like cancer. Small RNA, has no protein-encoding sequence, has been indentified to interfere with stability or translational ratio of mRNA. MiRNA is one of the small RNA family and has been analyzed about the synthesis, function and target genes. These researches lead exploitation of new nucleic drugs. Many researches have been reported for relationship between miRNA and rheumatoid arthritis (RA)/osteoarthritis (OA). MiR-146a and -155 were mainly reported for RA, miR-140 was mainly reported for OA including cartilage development. This article was summarized various analysis for miRNA with RA and OA.

• 日本臨床免疫学会の論文

著者

• 田中 陽子

  東京医科歯科大学 認知行動医

• 浅原 弘嗣

  東京医科歯科大学　医歯学総合研究科　システム発生・再生医学分野

関連論文

• Joint and microRNA
• 関節と microRNA

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