In Vitro Susceptibility of Mycoplasma hyopneumoniae Field Isolates and Occurrence of Fluoroquinolone, Macrolides and Lincomycin Resistance
スポンサーリンク
概要
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A total of 159 Thai isolates of Mycoplasma hyopneumoniae isolated from pneumonic lungs of pigs during 2006–2011 were investigated for their in vitro susceptibility to 12 antimicrobial agents. Low activity of chlortetracycline was indicated by the MIC range from 3.12–100 mcg/ml and MIC90 of 50 mcg/ml. Seventy-six isolates showed resistance to enrofloxacin, whereas 2 isolates showed resistance to macrolides and lincomycin. In addition, a point mutation at A2058G was revealed by sequence analysis of 23S ribosomal RNA in both isolates. The present results confirmed the rapid increase of resistant M. hyopneumoniae isolates against chlortetracycline, enrofloxacin, macrolides and lincomycin in Thailand. Selection of drugs to control swine diseases in Thailand must be done more prudently in consideration of reducing the antimicrobial resistance.
著者
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Kobayashi Hideki
National Institute of Animal Health
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PATHANASOPHON Pornpen
National Institute of Animal Health
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YAMAMOTO Koshi
Department of Agriculture, Tokyo University of Agriculture, Tokyo 156–8502, Japan
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PATHANASOPHON Pornpen
National Institute of Animal Health, Bangkok 10900, Thailand
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KISHIMA Masato
Diseases Investigation Center, Subang, West Java, Indonesia
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THONGKAMKOON Pacharee
National Institute of Animal Health, Bangkok 10900, Thailand
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NARONGSAK Watcharachai
National Institute of Animal Health, Bangkok 10900, Thailand
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