Two New Diterpenoids from Cell Cultures of Salvia miltiorrhiza
スポンサーリンク
概要
- 論文の詳細を見る
A new spiroketallactone, epi-danshenspiroketallactone A (1) and a new C18-norditerpenoid, normiltioane (2) along with 21 known compounds, were isolated from cell cultures of Salvia miltiorrhiza. Their structures were elucidated on the basis of extensive spectroscopic analyses. In the in vitro assays, the compounds 9−11, 21−23 exhibited the significant antitumor activity with the IC50 ranges of 1.0–8.3 µ<span style="font-variant: small-caps;">m</span>.
著者
-
Dai Jungui
State Key Lab. Of Bioactive Substances And Functions Of Natural Medicines Inst. Of Materia Medica Ch
-
Zhang De-wu
State Key Lab. Of Bioactive Substance And Function Of Natural Medicines & Key Lab. Of Biosynthes
-
Zou Jian-hua
State Key Lab. Of Bioactive Substance And Function Of Natural Medicines & Key Lab. Of Biosynthes
-
Xie Dan
State Key Laboratory of Bioactive Substance and Function of Natural Medicines & Key Laboratory of Biosynthesis of Natural Products, Ministry of Public Health, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical Co
-
Liu Xiao
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
-
Zhang De-Wu
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
-
Tao Xiao-Yu
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
-
Chen Ridao
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
関連論文
- Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma
- Clusterin as a predictor for chemoradiotherapy sensitivity and patient survival in esophageal squamous cell carcinoma
- Overexpression of AlB1 predicts resistance to chemoradiotherapy and poor prognosis in patients with primary esophageal squamous cell carcinoma
- Biotransformation of a Taxadiene by Ginkgo Cell Cultures and the Tumor Multi-Drug Resistant Reversal Activities of the Metabolites
- Comparative analysis of duplicated sox21 genes in zebrafish
- Antitumoral efficacy by systemic delivery of heparin conjugated polyethylenimine-plasmid interleukin-15 complexes in murine models of lung metastasis
- Two New Terpenoids from Endophytic Fungus Periconia sp. F-31
- Butyrolactone and Cycloheptanetrione from Mangrove-Associated Fungus Aspergillus terreus
- Two New Diterpenoids from Cell Cultures of Salvia miltiorrhiza