Studies on Oral Galactose Tolerance Test Using Galactose Dehydrogenase Method:II: Determination of Galactose in Urine during Oral Galactose Tolerance Test

概要

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The galactose excretions in urine during oral galactose tolerance test were examined in cases of 17 normal, 31 diabetes and 32 liver diseases.<BR>Galactose excretions in urine for 2 hours in diabetes and various liver diseases were remarkable as compared with normal subjects, especially liver cirrhosis showed the most conspicuous excretion of galactose in urine.<BR>There was no significant difference among normal, diabetes and various liver disease, in excreating amounts of urine for 2 hours. The changes of urinary protein, ketone bodies, urobilinogen and glucose during oral galactose tolerance test were semi-quantitatively examined. Protein test was unchanged and ketone bodies test turned to positive only in each 1 case in diabetes and liver diseases. Urobilinogen test generally turned to negative after galactose loading except 2 cases in liver diseases, it should be considered to depend on dilution of urine concentration after loading. Glucose test in urine after loading turned to positive in 7 cases out of 17 cases in normal subjects. This positive grade was higher percentage in diabetes and liver diseases than in normal. On the urinary excreting amount of glucose and galactose, slightly positive correlation was observed in urine after galactose loading.
Japan Society of Clinical Chemistryの論文