Clinical Prognosis of Early Repolarization on Electrocardiography in Survivors after out of Hospital Cardiopulmonary Arrest

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Purpose: An early repolarization (ER) in inferior leads on electrocardiography (ECG) has been shown to be associated with an increased risk of ventricular arrhythmias. However, ECG findings on ER after resuscitation of cardiopulmonary arrest (CPA) subjects are unknown. Methods: Of 448 consecutive subjects with out-of-hospital CPA for the last 2 years, 118 subjects were resuscitated. Among them, 64 subjects (35 male, 76±14 years) who had no evident of acute ischemia or vascular deseases were evaluated and divided into two groups: 1) with early repolarization in inferior leads 2) without those findings. Baseline demographic, clinical and electrocardiographic characteristics were analyzed. Early repolarization was defined as >0.1 mV J-point elevation of the QRS-ST junction in at least two leads in inferior leads as QRS slurring or notching, and was stratified according to the degree of J-point elevation (>0.1 mV or >0.15 mV). Results: ER was detected in 23 subjects. There was no significant difference in patient baseline characteristics between two groups. However, 11 subjects with more than 0.15 mV J-point elevation of Group 1 had markedly lower in survival time than the Group 2 (2.8±3.7 vs 8.8±17.1 [days], P=0.045), and more than 5 days survival after resuscitation was significantly increased in Group 2 compared with those subjects in Group 1 (29 vs 18 [%], P=0.043). Conclusions: Greater degree of early repolarization in the inferior leads of ECG after resuscitation might suggest the poor prognosis in the CPA subjects.

Clinical Prognosis of Early Repolarization on Electrocardiography in Survivors after out of Hospital Cardiopulmonary Arrest

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