Therapy-Related Pure Erythroid Leukemia with Hepatic Infiltration and Hemophagocytic Syndrome
スポンサーリンク
概要
- 論文の詳細を見る
Pure erythroid leukemia (PEL) is an extremely rare disorder characterized by neoplastic proliferation of immature erythroblasts. A 66-year-old man, who had received chemoradiotherapy for hypopharyngeal cancer, was admitted because of pancytopenia. Bone marrow was infiltrated with 81% proerythroblasts positive for CD71 and CD235a. An increased number of macrophages with active hemophagocytosis was also present. Chromosome analysis showed hypodiploid complex abnormalities. The patient died of progressive disease despite induction chemotherapy. Erythroblastic infiltration into the liver and hemophagocytosis in the spleen were found at autopsy. Therapy-related PEL with hemophagocytic syndrome and hepatic infiltration of PEL has never been reported.
- 社団法人 日本内科学会の論文
著者
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Okamura Atsuo
Division Of Hematology Department Of Medicine Kobe University Graduate School Of Medicine
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Yamamoto Katsuya
Division Of Hematology Department Of Medicine Kobe University Graduate School Of Medicine
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Yokozaki Hiroshi
Division Of Pathology Department Of Pathology And Microbiology Kobe University Graduate School Of Me
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Yakushijin Kimikazu
Division Of Medical Oncology/hematology Department Of Medicine Kobe University Graduate School Of Me
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Inui Yumiko
Division Of Medical Oncology/hematology Department Of Medicine Kobe University Graduate School Of Me
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Funakoshi Yohei
Division Of Medical Oncology/hematology Department Of Medicine Kobe University Graduate School Of Me
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Matsuoka Hiroshi
Division Of Medical Oncology/hematology Department Of Medicine Kobe University Graduate School Of Me
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Minami Hironobu
Division Of Medical Oncology/hematology Department Of Medicine Kobe University Graduate School Of Me
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Takeuchi Mai
Division of Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Japan
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Funakoshi Yohei
Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
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Minami Hironobu
Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
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Yakushijin Kimikazu
Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
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Okamura Atsuo
Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
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