Streptococcus pneumoniae-Associated Hemolytic Uremic Syndrome in a Splenectomized Adult Patient
スポンサーリンク
概要
- 論文の詳細を見る
A 62-year-old splenectomized woman was admitted because of upper respiratory tract symptoms, general fatigue, and purpura. Laboratory data demonstrated microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure, and a positive Streptococcus pneumoniae (SP) urinary antigen test. A renal biopsy showed thrombotic microangiopathic changes. She was diagnosed with hemolytic uremic syndrome (HUS) secondary to SP infection. Methylprednisolone pulse therapy in addition to antibiotic therapy led to prompt improvement of her symptoms and laboratory abnormalities. This is the first adult case of SP-associated HUS successfully treated without hemodialysis. SP infection should be considered as a causative etiology in all splenectomized patients with HUS.
- 社団法人 日本内科学会の論文
著者
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Sawada Kenichi
Department Of Hematology Nephrology And Rheumatology Akita University Graduate School Of Medicine
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Kuroki Jun
Department Of Internal Medicine Yuri-kumiai General Hospital
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Komatsuda Atsushi
Department of Health and Environmental Sciences, Graduate School of Medicine Kyoto University
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Wakui Hideki
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine
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Wakui Hideki
Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Japan
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Asakura Kenichi
Department of Internal Medicine, Yuri Kumiai General Hospital, Japan
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Maki Nobuki
Department of Internal Medicine, Yuri Kumiai General Hospital, Japan
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Ohtani Hiroshi
Akita Kumiai General Hospital, Japan
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Nishinari Tamio
Department of Internal Medicine, Yuri Kumiai General Hospital, Japan
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