Simultaneous Development of Acute Disseminated Encephalomyelitis and Guillain-Barré Syndrome Associated with H1N1 09 Influenza Vaccination
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概要
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A 36-year-old man was admitted to our hospital because of urinary retention and muscle weakness affecting all 4 limbs after receiving a H1N1 09 influenza vaccination. Magnetic resonance imaging demonstrated multiple lesions in his brain and spinal cord. Furthermore, nerve conduction study showed acute sensorimotor neuropathy, and anti-GM2 antibodies were detected in his serum. Based on the temporal association and exclusion of alternative etiologies, we made a diagnosis of acute disseminated encephalomyelitis (ADEM) and Guillain-Barré syndrome (GBS). To our knowledge, this is the first case of co-morbid ADEM and GBS after influenza vaccination with positive anti-ganglioside antibodies.
著者
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Hoshino Takao
Department Of Gastroenterology Akita Kumiai General Hospital
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Ohashi Takashi
Department Of Demyelinating Disease And Aging National Institute Of Neuroscience Ncnp
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Ito Eiichi
Department Of Neurology Higashi Nagoya National Hospital
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Uchiyama Yumiko
Department Of Neurology Tokyo Women's Medical University
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Hoshino Takao
Department of Neurology, Tokyo Women's Medical University, Japan
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Osawa Shunsuke
Department of Neurology, Tokyo Women's Medical University Yachiyo Medical Center, Japan
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Ito Eiichi
Department of Neurology, Tokyo Women's Medical University, Japan
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Ito Eiichi
Department of Cardiology, Niigata Prefectural Shibata Hospital
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