Response to Low-dose Bortezomib in Plasma Cell Leukemia Patients with Malignant Pleural Effusion and Ascites: A Case Report and a Review of the Literature
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概要
- 論文の詳細を見る
Pleural effusion or ascites complicating plasmacytoma is rare and has a poor prognosis. A 70-year-old man was diagnosed as plasma cell leukemia and one course of ranimustine-vindesine, melphalan, and prednisolone followed by melphalan and prednisone (MP) maintained a very good partial response. After MP he was diagnosed to have pleural effusion and ascites as a complication of the plasmacytoma. Low-dose bortezomib caused disappearance of the malignant effusion. The malignant effusions recurred after the end of the second course of bortezomib. High-dose dexamethasone vincristine, doxorubicin, cyclophosphamide, and prednisone yielded no benefit, the patient died of Aspergillus pneumonia.
- 社団法人 日本内科学会の論文
著者
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Imai Hidenori
Division Of Hematology Department Of Internal Medicine Juntendo University School Of Medicine
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Sekiguchi Yasunobu
Division Of Hematology Department Of Internal Medicine Saitama Medical Center
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Komatsu Norio
Division Of Hematology Department Of Internal Medicine Jichi Medical University
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Ichikawa Kunimoto
Division Of Hematology Department Of Internal Medicine Juntendo University School Of Medicine
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Wakabayashi Mutsumi
Division Of Hematology Urayasu Hospital Juntendo University School Of Medicine
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Noguchi Masaaki
Division Of Hematology Urayasu Hospital Juntendo University School Of Medicine
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Komatsu Norio
Division of Hematology, , Juntendo University Juntendo Hospital, Japan
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Sugimoto Keiji
Division of Hematology, Juntendo University Urayasu Hospital
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Sugimoto Keiji
Division of Hematology, Juntendo University Urayasu Hospital, Japan
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Shirane Syuichi
Division of Hematology, , Juntendo University Juntendo Hospital, Japan
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Sawada Tomonori
Clinical Laboratory, Juntendo University Urayasu Hospital, Japan
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Chigira Noriko
Clinical Laboratory, Juntendo University Urayasu Hospital, Japan
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