Acute Tubulointerstitial Nephritis with Multiple Organ Involvement Including Fatal Adrenalitis: A Case Report with Autopsy Findings
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概要
- 論文の詳細を見る
A 68-year-old woman with Alzheimer's disease developed renal dysfunction after starting carbamazepine for epilepsy. Although Ga-67 citrate scintigraphy strongly suggested interstitial nephritis, renal biopsy was not possible due to her overall state. At 61 days after admission, she died of unexplained shock. At autopsy, severe infiltration of T lymphocytes was noted, not only in the renal interstitium but also in the liver, lungs, and adrenal glands. Adrenal failure was a possible cause of shock. In carbamazepine-induced interstitial nephritis, multiple organ involvement including fatal adrenalitis should be considered.
著者
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Takeda Tetsuro
Department Of Education For Children With Health Impairments National Institute Of Special Education
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Miyazaki Shigeru
Department Of Internal Medicine Tokyo Teishin Hospital
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Okazaki Etsuo
Department Of Pathology Niigata City General Hospital
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Narita Ichiei
Department Of Internal Medicine Ii Graduate School Of Medical And Dental Sciences Niigata University
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Kazama Junichiro
Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Japan
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Aoyagi Ryuji
Department of Nephrology, Tachikawa General Hospital, Japan
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Koda Ryo
Department of Nephrology, Tachikawa General Hospital, Japan
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Narita Ichiei
Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Japan
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Takeda Tetsuro
Department of Nephrology, Dokkyo Medical University Koshigaya Hospital, Japan
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Koda Ryo
Department of Nephrology, Dokkyo Medical University Koshigaya Hospital, Japan
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Okazaki Etsuo
Department of Pathology, Tachikawa General Hospital, Japan
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