The effect with inhalation of radon water (Ikeda mineral spring) of a half life time on tissue perfusion.

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We previously found experimentally that the subcutaneous tissue perfusion rate was increased by about 16% upon inhalation of high concentration radon (13, 764-23, 743Bq/l).To clarify the effect of a lower concentration of radon water by mass spectrometry, the subcutaneous tissue perfusion rate was determined experimentally in rabbits using fourth-day radon water of a 3, 519-6, 710Bq/l concentration taken from a mineral spring.The subcutaneous tissue perfusion rate with inhalation of the radon water was 15.81±3.10ml/100g/min (mean±SD, n=10), which was similar to that with inhalation with physiological saline solution (15.96±3.09ml/1008/min, n=16). However, the subcutaneous tissue perfusion rate with inhalation of more highly concentrated, first-day, radon water (8, 641-17, 366Bq/l) was 20.76±3.58ml/100g/min (n=16), being significantly higher (p<0.01) than that with water at lower radon concentration.Further studies are needed on the effect of radon water in relation to the hormesis with low dose of radiation.