人工炭酸浴に関する研究-1-炭酸泉の有効炭酸濃度について

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It was found that no effect of increase in dermal blood flow depended solely on HCO3- or CO32-, but on CO2 gas dissolved in water.The artificial CO2 bath was prepared with sodium bicarbonate and citric acid, mixing simply in plain water at 38-40°C.Thermal efficacy was confirmed by a rise in temperature of oral, finger tip and forehead respectively, and by a high transepidermal water loss (TWL) in consequence of increase in dermal blood flow, compared to a plain bathing.A remarkable effect in artificial CO2 bathing of 400-800ppm has been well-known clinically, however, a substantial increase in dermal blood flow has observed with artificial CO2-bathing of 59.8ppm or greater in this study, so that a CO2-bathing using the preparation would be popularized.
一般社団法人日本温泉気候物理医学会の論文