Effect of anesthetized antral mucosa on anti-peristaltic discharge.

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The origin of anti-peristaltic discharge occured in the distal stomach of canine after transection followed by end-to-end anastomosis is uncertain. The purpose of this paper is investigate electromyographycally whether the mucosa of the distal stomach effects on occurence of anti-peristaltic discharge.<BR>By appling lidocaine to the lumen of the distal stomach after transection followed by end-to-end anastomosis, the retardation of propagation velocity of normo-peristaltic discharge and the decrease of frequency of anti-peristaltic discharge were noted on the antrum.<BR>On respect of frequency of anti-peristaltic discharge, the findings above were remarkable in the high appearant group (5 dogs; ≥80%) compared with low appearant group (2 dogs; ≤60%).<BR>Conclusively, it was suggested that the occurrence of anti-peristaltic discharge was related to the enteric nervous system in the mucosa and/or submucosa.