Asymmetric reduction with C1- and C2-symmetric NADH model compounds containing chiral 1,1'-binaphthyls.

スポンサーリンク

概要

• 論文の詳細を見る

• The present study deals with Mg-catalyzed asymmetric reduction of ethyl benzoylformate by the use of C<SUB>2</SUB>-symmetric NADH model compounds in which axial dissymmetry (chiral 1, 1′-binaphthyl derivatives) was introduced as a chiral source for the first time and the results were compared with those obtained by the corresponding C<SUB>1</SUB>-symmetric models bearing the same chiral center. Better e.e.'s of the reduction product were obtained by the use of NADH models having C<SUB>2</SUB>-symmetry than does the corresponding C<SUB>1</SUB> symmetric ones. Further, the kind of bonding as well as the distance between chiral binaphthyl and the reaction center affected the stereochemical course of hydrogen transfer.

• 公益社団法人 日本化学会の論文

著者

• Baba Naomichi

  Institute For Chemical Research Kyoto University

• WATANABE Motoshi

  Institute for Chemical Research, Kyoto University

• INOUYE Yuzo

  Institute for Chemical Research, Kyoto University

• AMANO Masaki

  Institute for Chemical Research, Kyoto University

関連論文

• Enzymatic Resolution of Racemic Hydroperoxides in Organic Solvent(Organic Chemistry)
• Asymmetric Epoxidation of Cyclic Enones under Chiral Phase Transfer Conditions(Organic Chemistry)
• Asymmetric reduction with C1- and C2-symmetric NADH model compounds containing chiral 1,1'-binaphthyls.
• NADH Model Reaction: Asymmetric Reduction of Nonactivated Carbonyl Compounds with N-Anionized Hantzsch Ester
• Synthesis of Chiral NADH Model Compounds Containing a Sulfur Atom and Their Asymmetric Reduction
• Synthesis of amino compounds under phase transfer conditions.
• Stereochemical Behavior of an NADHModel Compound Carrying L-Prolinamide at 3, 5-Positions
• Asymmetric Photocyclization of Nitrone at Chiral Binding Site of Cyclodextrin in the Presence of Amino Acid
• Asymmetric Reduction by an NADH Model Compound with L-Prolinamide in the N1-Substituent
• Asymmetric Reduction with Bis(NADH) Model Compounds
• Effect of complexation by crown ethers on anisochrony of diastereotopic groups in NMR spectra.
• Stereochemistry of 1, 3-Eliminative Cyclopropanation
• Absolute Configuration of 3-Amino-1-phenylbutane
• Absolute Configuration of Some Chiral Cyclopropanes

もっと見る 閉じる

スポンサーリンク