Preparation and properties of oligocytidylates with 2'-5' internucleotide linkage.

スポンサーリンク

概要

• 論文の詳細を見る

• Oligocytidylates upto a pentamer were prepared by lead(II) ion catalyzed polymerization of cytidine 5′-phosphorimidazolide in aqueous solution. 2′–5′ internucleotide linkage was preferentially formed. The yields of the 2′–5′ linked dimer, trimer, tetramer and pentamer were 17.0, 5.5, 1.9, and 0.7%, respectively. Some of their properties were studied by NMR, CD, UV, and chromatography and compared with the corresponding 3′–5′ linked oligomers which were prepared enzymatically.

• 公益社団法人 日本化学会の論文

著者

• OHNO Masaji

  Faculty of Pharmaceutical Sciences, The University of Tokyo

• Ohno Masaji

  Faculty of Pharmaceutical Sciences, University of Tokyo Hongo

• Sawai Hiroaki

  Faculty of Pharmaceutical Sciences, University of Tokyo Hongo

関連論文

• Asymmetric Hydrolysis of Prochiral Dimethyl 3-Benzyloxycarbonylaminoglutarate with Microorganisms. Preparation of (S)-3-Amino-4- methoxycarbonylbutyric Acid for the Synthesis of Carbapenem and Negamycin Antibiotics
• Preparation and properties of oligocytidylates with 2'-5' internucleotide linkage.
• Synthesis of oligoinosinates with 2'-5' internucleotide linkage in aqueous solution using Pb2+ ion.

スポンサーリンク