Nonsteroidal antiinflammatory drugs. V The crystal and molecular structure of (.+-.)-(2S*)-2-(4-((1S*,2R*)-2-hydroxycyclopentylmethyl)-phenyl)propionic acid.

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概要

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• The crystal structure of the title compound was determined by X-ray diffraction techniques and was refined to a final R index of 0.094 for 1249 reflections. The cyclopentane ring takes a half-chair conformation in which the two substituents are attached at equatorial positions. The molecules form centrosymmetric tetramers by the two hydrogen bonds through the carboxyl and hydroxyl groups.

• 公益社団法人 日本化学会の論文

著者

• Sato Sadao

  Analytical And Metabolic Research Laboratories Sankyo Co. Ltd.

• Tamura Chihiro

  Analytical and Metabolic Research Laboratories, Sankyo Co. Ltd.

• Hata Tadashi

  Analytical and Metabolic Laboratories, Sankyo Co., Ltd.

• Hata Tadashi

  Analytical and Metabolic Research Laboratories, Sankyo Co. Ltd.

• Sato Sadao

  Analytical and Metabolic Research Laboratories, Sankyo Co. Ltd.

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