57. 脳血管攣縮に対するinduced hypertensionについて

概要

論文の詳細を見る
Effectiveness of dopamine- or dobutamine-induced hypertension therapy (DIH) was studied in thirty patients who developed symptomatic vasospasm following early surgery of ruptured intracranial aneurysms.Twenty-four patients (80%) of them showed significant improvement in neurological function. Posttreatment angiography was carried out in seventeen patients and proved a resolution of arterial spasm in sixteen of these patients. In a few patients, CT scan taken after the treatment, demonstrated disappearance of low density area suggestive of ischemic lesion. The DIH should be commenced as early as possible especially within 24 hours from the onset of ischemic symptoms. Systolic blood pressure should be maintained adequately for sufficient periods of time. The mortality and morbidity of the patients complicated by symptomatic vasospasm could be improved by DIH combined with early operation for aneurysms.
The Japanese Society on Surgery for Cerebral Strokeの論文