IN VITROの糖代謝に関する基礎的研究 (第一編)

概要

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The present paper is dealt on basic investigation on the seasonal influences and the correlation between the initial glycogen level and the ability of glucose utilization. The following results were obtained, 1. The glycogen contents of the rat diaphragm in winter were generally higher than in summer time. 2. The glucose utilization of rat diaphragm in summer has been more advantageous than in winter. 3. It has been shown that in summer the rate of glycogen synthesis ran parallel to the rate of glucose utilization of rat muscle. 4. The ability of the glycogen synthesis became lower in inverse proportion to the increase of the initial glycogen level, and occassionally, glycogenolysis has been seen when an initial glycogen level was markedly elevated. 5. A relation between the initial glycogen content and the glucose utilization could not be demonstrated in all the cases. 6. It should be emphasized that from the foregoing results any investigation if studied under in vitro, the experimental procedures must be carried out under an identical environmental situation and the codition in order to obtain accurate information.
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