膝関節の知覚神経終末からの位置覚の放電及び人工的関節水腫における放電の変化についての実験的研究
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概要
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It was possible to record the single unit discharges associated with knee movement from split dorsal root of toad in which the skin and muscle of lower limbs were removed. Two kinds of discharges were recognized at the passive movement of the knee-joint: i, e, rapidly and slowly adaptating discharges. The former were induced mainly during the movement and adaptated rapidly after cease of movement and were responded equivalently by extension or flexion of the joint. The latter continued discharges after cease of movement. Frequencies of latter discharges in adaptated situation were varied depending upon the receptors and the angle of the joint. Each receptor responded in a certain range of angle and maximally at a difinit angle. Therefore each receptor respond to some range of angle (activity range) . Two kinds of activity ranges recognized. One was narrow and the other was wide responding to nearly allranges of the joint movement. The slowly adaptating discharge also varried in frequency during movement. However those of discharge were varried by the direction of the movement since a definit discharge appeared in a definit angle of joint. From those results, it was suggested that the rapidly adaptating discharge may give the information of movement and that the slowly adaptating one the information of the position and the direction of movent of the joint. Both receptors of rapidly and slowly adaptating discharges were distributed to be respond to all angles of the joint. In hydrops caused by injection of physiological saline solutn into the joint, the slowly adaptating discharge were responded by changing the intra-joint pressure. Optimal pressure providing maximal discharge frequency was obtained and differed from receptor to receptor ; some responded to a responded to a relativly narrow range of a variation in pressure while the other to a wide range. The former had a higher frequency and changed more markedly in response to a variation in pressure than the latter. Another low amplitude discharges appeared in chronic hydrops initially or by rising the intra-joint pressure. This kind of discharge disappeared by intra-joint application of xylocaine, therefore this might be induced by some change in receptor of chronic hydrops and inform pain sensation of joint.
- 学校法人 昭和大学・昭和医学会の論文