小児科領域に於けるブドウ球菌感染について-2-正常小児血液及び母血,臍帯血並びに母乳中のコアグラーゼ抗体に関する検討
スポンサーリンク
概要
- 論文の詳細を見る
With a view to unvail the substance of staphylococcal infections and the responses on the part of a living body, 101 healthy children (from neonatal period to 15 years of age olds) and 28 healthy adults (over 16 years old) were studied for the measurement of antibody value of seven kinds of Coagulase contained in serum, mother's serum, umbilical cord serum and breast milk. Coagulase is supposed to be one of the antibodies of staphylococcal infections.<BR>The experiment revealed the following results:<BR>1) Observed from the viewpoint of age, the antibody value of Coagulase is highest among newborn babies, and it gradually goes down as months pass reaching lowest when the babies are from five to twelve months old.<BR>2) Cases of negative phase in antibody production are fewest among 16-20 years old group (0 %), 11.8 percent among 11-15 years olds, 23.8 percent among upward of 20, 31.3 percent among 4-6 years olds, 55.5 percent among 1-3, and 85.7 percent among from nine to twelve months old babies. In general the, younger the person is, the more cases of negative phase in antibody production.<BR>3) Coagulase antibody contains the highest percentage of Coagulase type V (27.9 %) and the lowest percentage of type I (6.95 %) . It was found that Coagulase antibody varies according to the types of Coagulase.<BR>4) As to the relations between respective groups of Phage and content percentage of respective types of Coagulase antibody, Phage type III contains the highest percentage of Coagulase antibody (72.1 %), and Phage type I showed a low percentage (24.8 %) .<BR>5) The investigation of frequency of staphylococcal invasion reveald that Coagulase antibody No. 1 is a principal invader (30.3 %) and that the older the person grows, the more types of Coagulase antibody and more frequent staphylococcal invasions are noted.<BR>6) The experiment revealed that respective groups of Phage showed higher Coagulase antibody titer with the increase of age.<BR>7) The experiments of 20 species of mother's blood, umbilical cord blood and breast milk revealed that the antibody titer of Coagulase was highest in mother's blood and that of umbilical cord blood is approximately 1/2.4 of that of the former, while breast milk showed approximately one-thirthieth of the antibody titer of mother's blood and umbilical cord blood showed about one-eleventh.<BR>8) The high titer of Coagulase antibody in infancy is supposed to be resultant from the infants' receiving their blood from mother's blood and her umbilical cord blood which show high titer of Coagulase antibody.<BR>9) The distribution of antibody of all type of Coagulase in mother's blood, umbilical cord blood and breast milk showed no evident difference from that of normal persons.
- 学校法人 昭和大学・昭和医学会の論文
著者
関連論文
- 小児科領域におけるS-1108細粒剤の基礎的・臨床的総合評価
- 小児科領域におけるSY5555に関する検討
- 小児科領域に於けるブドウ球菌感染について-1-健康幼児からのブドウ球菌に関する研究 特に都市,無医村地区との比較に就いて
- 小児科領域に於けるブドウ球菌感染について-2-正常小児血液及び母血,臍帯血並びに母乳中のコアグラーゼ抗体に関する検討