ホルモン療法を受けている乳癌患者のQuality of Life(QOL)に関する基礎的研究

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Hormonotherapy is a treatment for breast cancer, the incidence of which has been recently increasing. Hormonotherapy is expected to reduce the size of the tumor but deteriorate the QOL by causing climacteric symptoms. In this study, the occurrence of climacteric symptoms due to hormonotherapy and associated psychological, physical, and social problems were evaluated. The 41 subjects aged 55.2 (5.0 years and 1.9 (1.4 years after surgery for breast cancer Were all undergoing hormonotherapy, 19 of whom had experienced menopause before hormonotherapy. Items including Kupperman's climacteric index and HADS index were investigated by semi-structured interviews. Symptoms were observed in about 61% of the subjects. Many of the symptoms were related to the shoulder and arm of the affected side. The mean total climacteric score was 20.5 (9.5, and the incidence of vasomotor neuropathy was high, probably because of suppression of ovarian function due to treatment. Positive correlations were observed between climacteric symptoms and the severity of anxiety and depression, suggesting a strong association between physical and mental symptoms. The subjects who did not have menopause before the treatment worried more about the economic burden of the treatment than those who did (p<0.05), and younger subjects more strongly felt they were causing trouble for the families (r0.554, p<0.01) . A program to provide appropriate support according to the age of the patient is necessary.

ホルモン療法を受けている乳癌患者のQuality of Life(QOL)に関する基礎的研究

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