扁桃悪性腫瘍の治療について

概要

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A clinical study was done on 99 patients with malignant tumor of the palatine tonsil. Histologically, 81 cases revealed a sarcoma including 73 reticulum cell sarcoma cases. The patients were treated by radiotherapy and surgery at Tokyo University Hospital through interdisciplinary collaboration during the period of 1964-1976.Radiotherapy was firstly applied to the primary lesion (81 cases) and metastasis (48 cases) of all of sarcoma patients except one whose gastric metastasis was treated by surgery alone. Surgery or systemic chemotherapy were combined to the primary of six cases and metastasis of seven.For all 18 carcinoma patients, irradiation was firstly given to the tonsil and metastasis (8 cases). Regional chemotherapy was combined to the primary of three patients and systemic chemotherapy to a metastasis of one. No surgery was applied in cases of carcinoma.The five-year survival rate was 57% in cases of sarcoma and 70% in cases of carcinoma.The following was concluded:For tonsillar sarcoma, irradiation to the primary lesion and metastasis is so effective that neither surgery nor chemotherapy is necessary.In cases of carcinoma, radiotherapy should be firstly applied to the primary and metastasis. Regional chemotherapy can be combined for a few radioresistant cases.
耳鼻咽喉科臨床学会の論文