気管呼吸の気道粘膜表面微細構造におよぼす影響に関する研究

概要

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The nasal, laryngeal and tracheal mucosa of the dog was studied with a scanning electron microscope and an X-ray microanalyser (EDX) after shunting air from the nasal passages by tracheal fenestration using a modified technique of Whicker et al. On the anterior third of the lateral wall, the nasal septum and localized regions of the subglottic area, the mucous membrane was composed of various types of non-ciliated cells such as squamous, low cuboidal and columnar epithelia. These areas, so-called inactive areas, were replaced by numerous ciliated cells about three months after tracheal fenestration. At the same time, the respiratory mucosa on the opposite side of the tracheal stoma was covered by stratified squamous epithelium following marked proliferation of goblet cells within the first two weeks after the operation. In addition, the same characteristic morphology of non-ciliated cells as in the above-mentioned inactive areas was observed on the peripheral mucosa right below the edge of the stoma.The respiratory epithelium was investigated with EDX. Phosphorus, sulfur and small amounts of calcium were found on the ciliated mucosa. On the non-ciliated mucosa, phosphorus and sulfur were found. On the squamous epithelium, phosphorus and much sulfer were found.
耳鼻咽喉科臨床学会の論文