上顎癌と癌胎児性抗原(CEA)

概要

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Fifty patients were examined in order to define the clinical value of carcinoembryonic antigen (CEA) in maxillary cancer.Plasma CEA levels of all cases were measured. At the time of testing, 37 of the 50 were tumor-bearing and the others were tumor-free more than six months after treatment.Plasma CEA level higher than 2.6ng/ml was estimated positive and 16 of the 37 patients who were tumor-bearing and none of the 13 patients who were tumor-free were positive.In 18 out of the 37 patients who were tumor bearing, tumor CEA levels were measured. In 30% of the cases studied, the tumor CEA level was higher than that in the mucous membrane of maxillary sinusitis.Correlation between the tumor CEA level and the plasma CEA level was observed.No significant findings were shown in immunohistological study.Plasma CEA levels in the patients with maxillary cancer correlated with the tumor volume and the tumor CEA level.Serial determination of plasma CEA levels may have some value in monitoring tumor metastasis.CEA in maxillary cancer seems to be much more affected with CEA-like substances.
耳鼻咽喉科臨床学会の論文