Inner Ear and Hormones.

概要

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The possible roles of several hormones such as aldosterone, vasopressin, atrial natriuretic peptide (ANP) and catecholamines in the inner ear are reviewed on the basis of recent research results, including our data. The presence of a mineralocorticoid type I receptor, Na-K ATPase and amiloride-sensitive Na+ channels in the cells involved in the secretion and absorption of endolymph, such as the marginal cells, suggest that aldosterone may control endolymph secretion and absorption. The involvement of vasopressin in the homeostasis of the endolymphatic system, which has been suggested by several lines of evidence, remains to be clarified. Recent results have also suggested that ANP may control the secretion and absorption of endolymph in the inner ear, regulate cochlear nerve function, and control inner ear blood flow. Finally, recent evidence also suggests that catecholamines may regulate the function of the endolymphatic sac.
耳鼻咽喉科臨床学会の論文