Neuro-Otological Distubance in HTLV-1 Associated Myelopathy.

概要

論文の詳細を見る
HTLV-1 associated myelopathy (HAM) is considered to be caused by Human T-lymphotrophic Virus Type 1 (HTLV-1), and is characteraized by slow progressive spastic paraparesis. Although sphincteric and sensory disturbances are observed as other major symptoms, disturbances of eye movement and hearing loss occur in some patients as minor symptoms. In order to clarify the neuro-otological abnormalities, we perfomed pure tone audiometry, auditory brainstem responses, and equilibrium tests in 12 patients. Eleven of them showed sensorineural hearing loss and one patient showed mixed hearing loss. On the auditory brainstem responses, 8 patients showed increases of I-III interpeak latency, and 5 patients showed increases of I-V interpeak latency. On positioning nystagmus tests, 1 patient showed rotatory nystagmus. On the eye tracking tests, 2 patients showed superimposed saccadic eye movements on sinusoidal curve and 2 other patients showed ataxic eye movements. On the caloric test, 1 patient showed unilateral CP. These facts suggest not only involvement of the spinal cord but also involvement of the brainstem, as reported previously.
耳鼻咽喉科臨床学会の論文