Clinical evaluation of eperisone H-Cl (Myonal) therapy for vertigo.

概要

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Eperisone H-Cl, which has been found to improve cerebral circulation and to act as a muscle relaxant, was used to treat 30 patients complaining of vertigo. The rate of effectiveness for vertebro-basilar insufficiency (13 patients) was 92.3%, and that for Meniere's disease (13 patients) was 76.9%. Eperisone was relatively effective for moderately intense vertigo, with the onset within 3 months. Rotating, floating and motion sensations decreased in most patients. On the other hand, the rates of effectiveness for hearing loss and tinnitus were low.In patients with peripheral vertigo, the overall effectiveness of Eperisone was significantly greater in those whose shoulder muscle pain was alleviated than in those whose shoulder pain persisted. This suggests that the muscle relaxant effect of Eperisone plays an important role in the treatment of peripheral vertigo, including Meniere's disease.
耳鼻咽喉科臨床学会の論文