Nasal provocation test with use of thread test for nasal secretion.

概要

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There are few ways to evaluate nasal allergy provocation tests objectively and quantitatively. The thread dying test method which was devised for lacrimation test (Kurihashi & Yanagihara) has been also used as a nasal secretion test (Kumazawa et al).The efficacy of this test was evaluated by nasal provocation tests of 10 patients with cryptomeria pollenosis and 10 normal individuals as controls. The test was compared with Okuda's gradings for nasal allergy. The effect of drug therapy (Tranilast) was also evaluated by this method and by Okuda's subjective gradings. The results showed that 70% of the patients experienced relief and that objective signs of improvement correlated fairly well with subjective symptoms (p<0.1). Okuda's subjective evaluation, however, did not correlate well with changes in subjective symptoms.