Two cases of ear cancer.

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Two cases of cancer of the middle ear and the deep external auditory meatus are reported.The first case was a 51-yr-old man with chronic ear discharge. He visited our clinic because of swelling of the preauricular area. A granulomatous tumor was discovered in the right external auditory canal and biopsied. It was found histolosically to be squamous cell carcinoma. He was treated with radical mastoidectomy with neck dissection, chemotherapy and irradiation, but died of recurrent tumor which invaded the dura mater.A 71-yr-old woman had had a diagnosis of cholesteatoma in childfood. She was treated in our clinic by radical mastoidectomy for acute exacerbation of the cholesteatoma. The pathological diagnosis was chronic inflammation. Five years later, she complained of postauricular swelling, and a radical mastoidectomy was done. Histological findings disclosed papilloma with hyperkeratosis. After the second operation, tumor grew rapidly in the auditory meatus and mastoid cavity. A third mastoidectomy was perfomred with resection of the chondral external auditory meatus. Matter exenterated from the mastoid antrum and middle ear was found to be squamous cell carcinoma. Cobalt therapy was planned, but she died of cachexia.The early descriptions of intrinsic cancer of the middle ear noted that it often followed long standing chronic otitis media. The estimated duration of otorrhea before a sudden change in symptoms suggested that carcinogenesis took more than 40 years in case 1 and more than 60 years in case 2, chronic inflammation may influence the development of cancer of the middle ear.

Two cases of ear cancer.

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