嗅神経芽腫の1症例

概要

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Olfactory neuroblastoma is an uncommon malignant tumor originating in the olfactory epithelium of the roof of the nose.Only 22 cases with the same disease have been reported in the Japanese literature.The purpose of this paper is to report one additional case.A 71-year-old man presented himself to our department in February 1981 with unilateral epistaxis and nasal obstruction.The diagnosis was eventually made three months later by electron microscopy. The most consistent fine structual findings were the presence of intracytoplasmic neurosecretary granules and neuritic processes.The patient was treated successfully with irradiation and partial resection. Bilateral cervical lymph node involvement soon set in and he died 8 months after initial treatment.
耳鼻咽喉科臨床学会の論文