Photodynamic Mutagenic Activity of Riboflavin for Transforming Deoxyribonucleic Acid and Accelerative Effect of Adenine
スポンサーリンク
概要
- 論文の詳細を見る
Riboflavin afforded the mutagenic effect on transforming deoxyribonucleic acid (DNA) from Bacillus subtilis through photodynamic action, and upon the addition of adenine to the irradiation mixture the mutagenic effect was greatly accelerated. Most of auxotrophic mutants among the transformants required tryptophan or tyrosine. The mutation was closely correlated with the photodynamic inactivation of the DNA, and it was suggested that both the inactivation and the mutation were caused by the selective photodegradation of guanine residues in DNA.
- 日本ビタミン学会の論文
著者
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細見 三郎
Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Osaka University
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溝口 正
Laboratory Of Biochemistry Faculty Of Pharmaceutical Sciences Osaka University
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溝口 正
Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Osaka University
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上原 喜八郎
Laboratory of Biochemistry, Faculty of Pharmaceutical Science, Osaka University
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