Hodgkin's Disease in Bone

概要

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The reported incidence of Hodgkin's disease in bone varies widely from 10.7% to 34.0%, and radiographic evidence may be found antemortem in approximately fifteen per cent of all cases of Hodgkin's disease. Three cases with bone lesions were found among eighteen patients of Hodgkin's disease in our hospital in recent four years.The first case was a boy, seven years of age, with several nodules in the left neck and involement of the first lumbar spine, which resulted in a wedge-shaped deformity by the collapes of the body. This case were treated by Endoxan and Trenimon, following by irradiation. Relief of the pain and arrest of the bone destruction were obtained.The next case was a woman, twenty-six years of age, with enlargement of several supraclavicular lymph-nodes and later destructive involvement of the fifth thoracal spine. Chemical controls produced some remissions and regressions of the adenopathy, even though temporarily.The another case was a man, twenty-seven years of age, with adenopathy of the left neck and involvement of the right 9th rib. Treatment of the patient, by several chemotherapeutic agents (Endoxan, Vincristine, 6MP, etc.) and local irradiation of the bone lesion, were proved to be respond in some degree, but the patient resulted in death.
西日本整形・災害外科学会の論文