A Case Report of Alkaptonuria

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In 1861, Baedeker discribed Alkaptonuria. In 1891, Volkow and Baumann published the original account of this disease for the first time.We reported here a case of Alkaptonuria which has recently come to our notice.Our case, 47-year-old male, complained of low back pain and spinal deformity.Radiographic examination of his spine showed Wafer-like change of the intervertebral discs, remarked narrowing of the interverbral spaces, marginal lipping of the vertebral bodiesand hypertrophy, of the spinous processes.We noticed that his urine turned black when it was left standing.
西日本整形・災害外科学会の論文