Scanning Electron Microscopic observations on Tumors of Bone and Soft Tissue

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We observed several kinds of bone and soft tissue tumor under the scanning electron microscope using the frozen resin cracking method and the ion etching technique.The details of finding were as follows.1. Giant cell tumor of boneMany spherical mitochondria (0.3-0.4μ in diameter) and bizarre nuclei were observed in the giant cell. Nuclear pores were seen at the surface of the nucleus of the endothelial cell.2. OsteosarcomaThe osteosarcoma cell was surrounded by collagen fibers, and occasionally contained solid and spherical structures about 1.0μ in diameter (possibly fat globules).3. Malignant fibrous histiocytoma of boneCollagen fibers surrounded the spindle-shaped fibroblastic cell. The nucleus shape was irregular.4. LiposarcomaSpherical fat globules about 0.8μ in diameter were observed in the cytoplasma of the lipdsarcoma cell.
西日本整形・災害外科学会の論文