Two cases of hyperparathyroidism.

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Two patients with hyperparathyroidism and cystic bone lesions were reported. Case 1: A 32-year-old female was admitted to our clinic because of right lower leg pain. Radiographs of the long bones showed cystic bone lesions and subperiosteal bone resorption was found in the hands. The right fibula had pathologic fracture. Laboratory investigations disclosed hypercalcemia (11.4mg/dl) and hypophosphatemia (1.8mg/dl). The serum alkaline phosphatase was 94 K-Au and the PTH level was 2.4ng/ml. The serum 1, 25-(OH)2-D3 level was 105.9pg/ml. A parathyroid chief cell adenoma was removed. Case 2: A 23-year-old female was admitted to our clinic because of right forearm pain. Radiographs showed groundglass appearance of the right humerus, radius, first metacarpus and proximal and distal phalanx. Laboratory studies showed normal serum calcium, phosphorous and alkaline phosphatase values. The serum PTH level was elevated to 4.9ng/ml. Resection and bone grafting was done. This case was recognized as polyostotic fibrous dysplasia associated with primary hyperparathyroidism.
西日本整形・災害外科学会の論文