Huge Lipoma with Cartilaginous and Osseous Metaplasia.

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Lipomas are the most common benign tumors, and in addition mature adipose tissue rarely shows cartilaginous or osseous metaplasia. This paper presents a rare case of lipoma showing areas of both cartilage and bone formation.A 17-year-old student presented to our hospital complaining of painless swelling over a large portion of the antero-lateral aspect of the right thigh, initially noted two years previously as a small swelling. It gradually increased to its present size. The tumor spontaneously appeared without any association with injury or symptoms of infection. The tumor was movable, but tenderness or local heat were not noted. Plain X-P disclosed a large radiolucent mass, with calcification or ossification at the center of the mass. The results of CT and MR imaging indicated the mass to posssibly be a large adiposelike tumor with calcification and ossification. The tumor, situated inter-muscularly among the rectus femoris muscle, vastus intermedius muscle, tensor fasciae latae muscle and vastus lateralis muscle, was surgically extirpated en bloc. Gross examination indicated a large mass, 15×7×5cm, soft, well circumscribed, and thinly encapsulated. A cut section was pale yellow, and bony masses were seen. Pathological examination data warranted a diagnosis of lipoma with cartilaginous and osseous metaplasia.