アメリカナマズ飼料中のビタミンKと抗血液凝固物質の関係〔英文〕

概要

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A series of studies on vitamin K relationships in channel catfish Ictalurus punctatus failed to demonstrate a requirement for vitamin K. A purified diet, which produced prolonged prothrombin time in chickens within two weeks, did not produce deficiency symptoms when fed to catfish for 30 weeks (over 2800% gain). Supplements of menadion sodium bisulfite, menadion dimethylpyrimidinol bisulfite, sulfaguanidine of sulfasuxidine did not have effects on growth rates, prothrombin times, hemoglobin or hematocrit levels. The feeding or injecting of dicumarol into catfish, which had been fed for 24 weeks the vitamin K deficient diet with sulfaguanidine, did not result in prolonged prothrombin times. The feeding of pivalyl resulted in prolonged prothrombin times which were not prevented by high levels of vitamin K. These results suggested that catfish have an extremely low (if any) requirement for vitamin K and raised the possibility that blood clotting mechanisms of catfish may be different from mammals or birds.
日本水産學會の論文