ニジマスおよびコイにおける酸化防止剤ジブチルヒドロキシトルエン(BHT)の吸収,分布および代謝〔英文〕

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The absorption, distribution, and excretion of 14C-BHT in rainbow trout Oncorhynchus mykiss and common carp Cyprinus carpio were examined. The radioactivity was high, as measured by the method of whole-body autoradiography, in the gall bladder and adipose tissue of the two fish species injected intravenously. The radioactivity of the bile was high, as measured by the method of scintillation counting, only in the common carp administered orally. In the excretion profile of 14C-BHT in the bile of rainbow trout, the radioactivity was increasing with time, reached a maximum level at 4 days or one week and then decreased gradually. In the excretion profile of 14C-BHT in common carp, the radioactivity was quickly distributed in tissues at the beginning. After 4 days, the radioactivity was shown to decrease in bile, hepatopancreas, and kidney.
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