Gastric secretion during the various stages of gastric ulcer:Part III: Vagal influence in gastric secretion during the various stages of gastric ulecr

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The gastric secretory responses with tetragastrin were investigated in patients with endoscopically determined stages of gastric ulcer.<BR>1) The increased sensitivity with the stimulation of tetragastrin during the active stage of ulcer was demonstrated by administration of tetragastrin infusion.<BR>2) "Medical vagotomy" with hyposcine-N-butylbromide was applied during tetragastrin infusion. Followed to the medical vagotomy, acid and pepsin outputs were more decreased at the active stage than those at the other stages. A change in vagal tone during the various stages of gastric ulcer may have contributed to this observed difference in sensitivity.
財団法人日本消化器病学会の論文