抗結核薬の投与期間の実態について

概要

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The duration of chemotherapy of 416 pulmonary tuberculosis patients who were subjected-to the cooperative chemotherapy studies of RYOKEN in 1968, 1969 and 1972, was investi: gated.<BR>The survey revealed that the proportion of patients treated for more than 3 years was 39. 6% even in moderately advanced and previously untreated cases and 59. 3% in far advanced cases. The similar and even longer term chemotherapy was also seen in retreatment cases and in failure cases using primary drugs, and the patients who were administered drugs for more than three years occupied about eighty per cent.<BR>The duration of chemotherapy was longer, as the time of convertion of bacilli was delayed. In addition to this, X-ray findings, such as existence of cavity or type of cavity also showed a great influence to the duration of chemotherapy.<BR>It was thought that tuberculosis patients were treated for longer term unnecessarily, because the relapse in this subjects was very few regardless of the duration of chemotherapy.
日本結核病学会の論文