肺結核患者の遅延型皮膚反応

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PHA and PPD skin reactions, peripheral lymphocytes and monocytes of 114 patients with pulmonary tuberculosis hospitalized in our hospital were investigated in relation to the types of pulmonary tuberculosis, the duration of bacilli discharge, the presence or absence of cavities, and the administrations of RFP. The following results were obtained: 1. RFP-treated patients showed significant reduction in PHA skin reaction as compared with non-treated patients. 2. All of B, C and F types according to GAKKEN classification showed reductions in PHA skin reaction as compared with the control group, while D type showed a rather higher value. The same trend by the type of lesions was also seen in bacilli positive cases. According to NTA classification, the reaction tended to decrease in proportion to extent of lesions. 3. PHA skin reaction in cases with continuous bacilli discharge and cavities tended to de crease as compared with the control group 4. PPD skin reaction was found to be (-) or (?) in many cases with advanced lesions according to NTA classification, and the proportion of tuberclin negative or doubtful cases was higher among cavitary cases. 5. It was found that the stronger the PPD skin reaction, the stronger the PHA skin reaction. 6. Peripheral monocytes tended to decrease in accordance with the extent of lesions according to NTA classification, and the trend was more marked in cavitary
日本結核病学会の論文