肺結核強化化学療法中に多彩な初期悪化がみられた1症例

概要

論文の詳細を見る
It has been well noticed that a transient aggravation is observed during chemotherapy for tuberculosis, especially in patients who were treated with rifampicin (RFP). A 34 years old man with pulmonary and renal tuberculosis was treated with combined regimen composed of RFP, isoniazid, and streptomycin. Seven weeks after the initiation of chemotherapy, left pleural effusion and right paratracheal lymph nodes enlargement appeared. Because of negative findings of sputum for tubercle bacilli, we continued the same regimen. As a result, chest X-ray film revealed the improvement of pleural effusion and enlarged paratracheal lymphnodes. These findings suggest that the aggravation observed was not true one and they were a transient one.<BR>In conclusion, tuberculosis with a transient aggravation shoud be treated with the same regimen including RFP if tubercle bacilli are negative on culture.
日本結核病学会の論文