BCG 再接種の検討
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概要
- 論文の詳細を見る
Tuberculin sensitivity of school children aged 6 and 13 in Kyushu district was investigated in relation to the time of BCG revaccination. The number tested by tuberculin at 6 years of age was 13, 703 in whole Kyushu district excluding Okinawa and 16, 378 in Okinawa, and the number of tuberculin tested children aged 13 was 14, 481 and 15, 634, respectively.<BR>The tuberculin sensitivity of school children in Okinawa where BCG vaccination had never been carried out for pre-school children showed an exponential distribution (L-shaped distribution). Tuber culin sensitivity of children aged 6 in other Kyushu district showed a distribution pattern similar to that of Okinawa, though approximately 60% of them were BCG vaccinated below 4 years of age. The fact suggests that the tuberculin sensitivity among them was not influenced much by the previous first BCG vaccination, and the proportion of tuberculin positive reactors was rather small.<BR>The tuberculin sensitivity of children aged 13 in Kyushu district showed normal distribution and the proportion of positive reactors was much higher. The fact suggests the influence of BCG vaccination at 6 years of age to the tuberculin sensitivity at 13 years.<BR>Taking into consideration the above fact on post-vaccination tuberculin sensitivity and the fact that the risk of infection increases in puberty, we came to the conclusion that the first BCG vaccination should be done in earlier period after birth, preferably within 1 year after birth and latest at the age of 1, and the second vaccination at 13 years of age under the present tuberculosis situation in Japan.
- 日本結核病学会の論文