非定型抗酸菌に関する研究 : I. 特にPhotochromogensの生物学的性状およびマウスに対する病原性

概要

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In the past three years three strains of unclassified acid-fast bacilli were isolated fromthe sputum of patients with pulmonary disease in Kanto Central Hospital (Tokyo). For the identification of these organisms, various biological and biochemical test and animal experiments (mice) were used in this study. The following tests were performed: Cord formation, Preis test, Drug resistance test, Niacin test, Neutral red test, Auramin test, Catalase test, Peroxidase test, Urease test. Animal experiments: Mice were inoculated intravenously with approximately 0.3mg. of Dubos liquid medium, and sacrificed 2, 5 and 10 weeks after infection. Bacteriological properties of three strains is shown in Table 1. Its pathogenicity was strong for mice see Table 2, 3. From the experimental results, it can be supposed that three strains is an unclassifid acid-fast bacilli. According to Runyons classification, these strains are similar to the strain of Group 1 photo.(Kato strain) and Group III nonphoto.(Uchida and Kekke strains), but different from the strains reported previrusly by many investigators in respect of various properties.
日本細菌学会の論文