Studies on the Staphylococcus:IV. Biological characters and coagulase action of the small colony mutant of<I>Staphylococcus aureus</I>, resistant to streptomycin
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By culturing<I>Staphylococcus aureus</I>FDA 209P, Nos. 19, 31, and 36 strains in a neutralbouillon broth supplemented with 1, 000 r/ml of streptomycin, SM-small colony mutants were obtained. These mutants were classified into two groups according to the phase of their size, and their biological characters as well as coagulase action were studied. The results are as follows.<BR>1. As for the decomposition of glucose and lactose by these mutants there could be recognized no change of these sugars as with the parent strain, but in the case of decomposition of<I>d</I>-mannitol there was a tendency of delay.<BR>2. Coagulase action differed considerably according to different strains and also there was a phase of low resistance to sodium chloride.<BR>From these findings it has been deduced that the small colony mutant results from the changes in the metabolic functions ensuing the nutrient requirements necessitated by enzyme inhibitory action of streptomycin.
- 日本細菌学会の論文
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- Studies on the Staphylococcus:IV. Biological characters and coagulase action of the small colony mutant ofStaphylococcus aureus, resistant to streptomycin