野兎病菌の実験動物に対する研究補遺 : VIII. ウサギについての免疫実験
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The immunization of rabbits was realized following the inoculation of<I>Bacterium tularense</I>vaccines. The immunogenic potencies of the vaccines made from living organisms were higher than those made from killed culture.<BR>The pathological changes induced by the challenge of the organisms in the immunized animals were found slight and the distribution of the organisms in the lesions was sparse, as compared with that of control animals.<BR>Not all of the survived animals of the immunized group showed an extremely high agglutinin titer at the time of challenge but some of them showed a lower titer on the contrary. This seems to indicate that the agglutinin has some relation to the degree of animal protection but it has no direct relation to the protective substance against the infection with<I>Bacterium tularense</I>.
- 日本細菌学会の論文
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