抗酸菌フアージの生物学的性状に関する研究 : 続報1. 抗酸菌フアージの菌体への吸着および増殖に及ぼす表面活性剤の影響
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In order to reveal the host-mycobacteriophage relationships, the effects of four kinds of surface active agents on adsorption and multiplication of mycobacteriophage were examined. All experiments have been made using Jucho-B1 system as host- phage system.<BR>Non ionic surface active agent (Tween 80) inhibited adsorption of the phages to the bacilli and multi- plication of the phages. It is thought that inhibition of multiplication of this phage is caused by that of adsorption of the phage to the bacilli. Cationic surface active agent (Acetamine 24) inactivated free phage, but had little effect on adsorption and multiplication. Anionic surface active agent (Emahl O) inactivated free phage and inhibited adsorption, but did not multiplication. This is due to promotion of bacterial growth by Emahl O. Dual ionic surface active agent (Cellogen F) had no effect on free phage and adsorption of B<SUB>1</SUB> phage, but exhibited a weak inhibition of multiplication.<BR>Calcium ion promoted adsorption of micobacteriophage B<SUB>1</SUB> to the bacilli.
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