Synthesis and Assignment of Novel (125I)-Labeled 1.ALPHA.,25-Dihydroxyvitamin D3 Derivatives.

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概要

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• This paper describes the synthesis and structural assignment of novel 125I-l α, 25-dihydroxyvitamin D3 derivatives (1a) and (lb) labeled with 125I-Bolton-Hunter reagent [N-succinimidyl 3-(4-hydroxy-3-iodo [125I] phenyl)propionate] (1), which is known as a protein-labeling reagent, as tracers for radioimmunoassay (RIA). The radiospecific activities of these tracers (1a) and (lb) were calculated as 2, 200 Ci/mmol (81.4TBq/mmol).

• 財団法人 学会誌刊行センターの論文

著者

• Nakagawa Nobuaki

  Research Institute Of Life Science Snow Brand Milk Products

• Tanabe Miyuki

  Research Laboratories Asahi Chemical Industry Corporated

• NAKAGAWA Nobuaki

  Research Laboratories, Toyo Jozo Co., Ltd.

• HARADA Masaya

  Research Laboratories, Toyo Jozo Co., Ltd.

• ODAWARA Fumitomo

  Research Laboratories, Toyo Jozo Co., Ltd.

• IKUTA Shigeru

  Research Laboratories, Toyo Jozo Co., Ltd.

• OTANI Masaru

  Research Laboratories, Toyo Jozo Co., Ltd.

• TANABE Miyuki

  Research Laboratories, Toyo Jozo Co., Ltd.

関連論文

• Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor
• Synthesis and Biological Activity of a 1α, 25-Dihydroxyvitamin D_2 Analog Bearing an Amide Group in the Side-Chain
• Synthesis and Assignment of Novel (125I)-Labeled 1.ALPHA.,25-Dihydroxyvitamin D3 Derivatives.

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