Lesions of intestinal epithelium by ingestion of bean lectins in rats.

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概要

• 論文の詳細を見る

• Wistar rats were submitted to the action of active lectins from common dry beans (Phaseolus vulgaris) and from jack beans (Canavalia ensiformis, DC). Raw common bean was offered to the rats in an otherwise balanced diet to make 10% protein as the sole protein source. A single dose of 20 mg of jack bean lectin (concanavalin A) was given by gastric intubation. Half of the rats receiving raw bean died within 22 days of experiment. Histological findings showed ulceration and necrosis of the intestinal villi in the surviving rats. In some cases the lesions reached also the submucosa. Gastric intubation of concanavalin A caused intense scaling off in the apical portion of the villi.

• 財団法人 学会誌刊行センターの論文

著者

• Vidal Benedicto

  Department Of Cell Biology Institute Of Biology

• OLIVEIRA Admar

  Departamento de Planejamento Alimentar e Nutricão, Faculdade de Engenharia de Alimentos

• SGARBIERI Valdemiro

  Departamento de Planejamento Alimentar e Nutricão, Faculdade de Engenharia de Alimentos

• VIDAL Benedicto

  Departamento de Biologia Celular, Instituto de Biologia, Universidade Estadual de Campinas

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• Effect of Soaking Prior to Cooking on the Levels of Phytate and Tannin of the Common Bean (Phaseolus vulgaris, L.) and the Protein Value
• Lesions of intestinal epithelium by ingestion of bean lectins in rats.
• Pattern of Fecal Endogenous Nitrogen Excretion in Rats Fed Leguminous Diets.

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