Analysis of laboratory findings in 40 cases undergone salvage operation for advanced head and neck cancer followed by immediate reconstruction.

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In 40 cases that undergone salvage operation followed by immediate reconstruction with pectoralis major myocutaneous flap for head and neck cancer, we studied changes in the laboratory findings (serum albumin, transaminase, urea nitrogen, WBC, lymphocyte percentage, nutritional index) during 4 weeks after operation, together with correlation of patient's age with preoperative laboratory findings, and the correlation of the total blood loss during operation with postoperative laboratory findings. The following results were obtained. 1. ALB, nutritional index, and PLT were significantly lowered as compared with preoperative levels, while WBC increased significantly. The margin of fluctuations was mostly similar to the findings in the cases previously reported in the fields of abdominal surgery and thoracic surgery, and surgical stress seemed larger than expected. 2. Postoperative complications were often found in the cases not showing notable WBC increase right after operation, and in the cases showing low values of ALB, PLT for more than a week after operation. 3. The greater the blood loss during operation, the less increase of WBC right after operation, and low level of PLT persisted. However, correlation with Hb was not observed. 4. Blood transfusion during a week after operation did not significantly influence the changes of TP, ALB and Hb. 5. From the age distribution of the present study, obvious correlation between age and laboratory findings was not observed.
社団法人日本口腔外科学会の論文

Analysis of laboratory findings in 40 cases undergone salvage operation for advanced head and neck cancer followed by immediate reconstruction.

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